Applications Of Coordination Compounds In Medicine Ppt

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Cisplatin PtCl2NH32 is useful in treatment of cancer. Hardness of water EDTA.

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Chemistry of Coordination Compounds Applications of coordination compounds Coordination compounds are used for many applications.

Applications of coordination compounds in medicine ppt. Worlds Best PowerPoint Templates – CrystalGraphics offers more PowerPoint templates than anyone else in the world with over 4 million to choose from. Medicinal Applications of Coordination Chemistry focuses on the role that transition metals play in clinical applications. 61 Applications of Monodentate Complexes 62 Two Keys to the Stability of Transition Metal Complexes Hard and Soft Acids and Bases The Chelate Effect 63 Applications of Multidentate Complexes 64 Chelating Agents as Detergent Builders 65 Bioinorganic Applications of Coordination Chemistry Oxygen Transport Therapeutic Chelating Agents for Heavy Metals Platinum Antitumor Agents.

This is the only naturally occurring organometallic compound found in biology. Coordination compounds include such substances as vitamin B 12 hemoglobin and chlorophyll dyes and pigments and catalysts used in preparing organic substances. The application of this field to biomedical uses is dealt with in 5 chapters.

Extraction processes of gold and silver. EDTA is used in the estimation of Ca 2 and Mg 2 in hardwater. It is an interesting biomolecule in the sense that no other vitamin contains a metal ion.

Coordination compound By azim 2. EDTA is useful in treatment of poisoning by lead. Therefore they find a common place in industries for intense colourations.

Inorganic compounds have been used in medicine for thousands of years often without a known molecular basis for their mechanism of action and with little attempt to design them. Application of coordination compounds Coordination compounds are found in populating systems and have many utilizations in the place in industry and medical specialty. Purifications of metals.

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Coordination compound Complex compounds are a special class of compounds in which the metal atoms or ions are bound to a number of anions or neutral molecules. 3 4. An intriguing aspect of vitamin B 12 is the great stability of the metal-carbon.

A reversible chemical reaction in which one reaction is an oxidation and the reverse is a reduction. Metals can be purified by the formation and subsequent decomposition of their coordination compounds. Many coordination complexes have been used in medicine containing metals such as platinum cisplatin as anticancer chemotherapy drug gold as auranofin used for rheumatoid arthritis technetium and rhenium as radiopharmaceuticals used in imaging and radiotherapy ruthenium as anticancer drug gadolinium cobalt lithium bismuth iron calcium lanthanum gallium tin arsenic rhodium copper zinc aluminum lutetium vanadium manganese etc.

We describe a few example here and in the chemistry. Coordination complexes can undergo a variety of reactions including electron transfer ligand exchange and associative processes. Phthalocyanine is a class of coordination complexes that the dyes and pigments industry extensively use.

For example it isused to detect cupric ions in the salt when copper sulphate solution is mixed with aqueous ammonia a deep blue complex soluble in water is formed. The design of coordination metal complexes is not an easy task. Used as catalysts in many industrial processes.

The Ca 2 and Mg 2 ions form stable complexes with EDTA. For example in the coordination complex given by NiNH342 the coordination number of nickel is 4. Coordination Compounds in Biology Vitamin B 12 is an important coordination compound in biol-ogy.

Applications of Coordination Compounds Coordination compounds have specific colours. Importance and Application of Coordination Compounds. Coordination compounds contain a central metal atom surrounded by nonmetal atoms or groups of atoms called ligands.

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Coordination Compounds for Medicine and Biology The interaction of transition metal ions with biological molecules provides one of the most fascinating areas of coordination chemistry. Applications of coordination compounds. The of coordination compounds has importance in biological system the coordination compounds play a vital role in metallurgy and medicine.

Theyll give your presentations a professional memorable appearance – the kind of sophisticated look that todays audiences expect. The reaction of one or more ligands with a metal ion to form a coordination compound. The coordination number of the central atom in the coordination compound refers to the total number of sigma bonds through which the ligands are bound to the coordination centre.

Winner of the Standing Ovation Award for Best PowerPoint Templates from Presentations Magazine. Many cytotoxic metal complexes target DNA because of its importance in replication and cell viability. The organic chemist often deals with diamagnetic compounds which are.

In modern terminology these compounds are called coordination compounds. We describe a few illustration here and in the chemical science. Coordination compounds offer many binding modes to polynucleotides includ-ing outer-sphere noncovalent binding metal coordination to nucleobase and phosphate backbone 810 Metal Complexes as Drugs and Chemotherapeutic Agents.

Stable complexes with very small dissociation in solution are used for electroplating with silver and gold. Metals in pharmaceuticals have played an increasingly important role in medicine over the last century particularly in cancer therapy and diagnostic imaging methods. Application of coordination compounds Coordination compounds are found in living systems and have many uses in the homein industry and medicine.

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The complex KAgCN 2 is used for electroplating.

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